Thus, it is important to isolate and propagate SARS-CoV-2 strains from Turkish COVID-19 patients. Since then, more than 150,000 diagnosed patients have been reported, showing the urgent need for vaccine studies and antiviral drug discoveries. The first diagnosed patient in Turkey was announced by the Ministry of Health on March 11, 2020. The novel SARS-CoV-2 is the virus behind the pandemic outbreak originating from China (Zhou et al., 2020) a large number of SARS-related coronaviruses (SARSr-CoVs and this recent coronavirus outbreak (COVID-19) presents enormous challenges for global health. SARS-CoV-2 is the seventh coronavirus known to infect humans SARS-CoV, MERS-CoV, and SARS-CoV-2 can cause severe disease, whereas HKU1, NL63, OC43, and 229E are associated with mild symptoms (Andersen et al., 2020). It is a positive-strand RNA virus (family: Coronaviridae), showing high homology with SARS-CoV and bat coronavirus (Zheng 2020 Liu and Li, 2020). New coronaviruses are likely to occur periodically in humans, considering the high prevalence and wide distribution of coronaviruses, the large genetic diversity and frequent recombination of genomes, common interspecific infections, and rare outbreaks (Wong et al., 2015 Cui et al., 2019).The novel coronavirus pneumonia, which was named later as coronavirus disease 2019 (COVID-19), is caused by the severe acute respiratory syndrome coronavirus 2, namely SARS-CoV-2 (Holshue et al., 2020).
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